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GHK-CU

The Copper Beauty Peptide | Copper Peptide - Skin Regeneration & Anti-Aging Compound

What is GHK-Cu?

GHK-Cu is a naturally occurring copper tripeptide found in human plasma, saliva, and urine. Plasma levels decline from ~200 ng/ml at age 20 to ~80 ng/ml by age 60. Research shows it affects 31.2% of human genes and promotes wound healing, collagen synthesis, and anti-aging effects.

The Copper Beauty Peptide GHK-Cu is a naturally occurring copper complex that acts as a "reset button" for your skin and connective tissues. It works by signaling your DNA to produce more collagen and elastin while also acting as a powerful protector against inflammation and aging.

Key Benefits

Enhanced collagen production, improved skin elasticity, reduced fine lines and wrinkles, accelerated wound healing, hair growth stimulation, convenient daily application.

  • Skin Tightening: Significantly improves skin elasticity and reduces sagging.

  • Wrinkle Reduction: Smooths out fine lines by thickening the skin's foundation.

  • Hair Growth: Stimulates hair follicles to produce thicker, fuller hair.

  • Fast Wound Healing: Excellent at repairing skin damage, including scars and sun damage.

  • Antioxidant Power: Protects cells from the "rusting" effects of pollution and UV rays.

  • Gut Health: Has shown potential in repairing the protective lining of the stomach.

Quick Start Guide

Typical Dose

  • 1-2mg

How Often

  • 1x daily

Where to Inject

  • Subcutaneous: abdomen, thigh, or upper arm

Injection Timing

  • Morning or evening consistently

Effects Timeline

  • 2-4 weeks for skin, 4-8 weeks for hair

Storage

  • Refrigerate at 2-8°C, use within 30 days of reconstitution

Cycle Length

  • 8-12 weeks

Break Between

  • 4-6 weeks

Research Indications

🟢 Anti Inflammatory - Most Effective

Systemic Anti-Aging

Provides comprehensive anti-aging effects through systemic circulation, reducing inflammation and oxidative stress throughout the body

Immune Modulation

Regulates inflammatory cytokine production and promotes balanced immune responses for optimal healing and health

Tissue Protection

Protects tissues from damage through powerful antioxidant mechanisms and enhanced cellular repair processes

🔵 Skin Regeneration - Effective

Deep Collagen Stimulation

Systemic delivery provides deep dermal collagen stimulation beyond what topical application can achieve

Accelerated Wound Healing

Injectable form shows superior wound healing acceleration with enhanced cellular migration and proliferation

Comprehensive Skin Repair

Addresses aging from inside out with improved skin elasticity, firmness, and overall appearance

⚪️ Hair Growth - Moderate

Follicle Revitalization

Systemic delivery provides nutrients and growth factors to hair follicles throughout the scalp

Circulation Enhancement

Improves blood flow to scalp and hair follicles for enhanced growth and thickness

Hormonal Balance

May help balance hormones affecting hair growth through systemic anti-inflammatory effects

What to expect

  • Week 1-2: Improved energy and skin hydration

  • Week 3-4: Enhanced skin texture and reduced inflammation

  • Week 6-8: Visible improvement in skin firmness and elasticity

  • Week 8-12: Comprehensive anti-aging effects

  • Hair growth: 4-8 weeks for initial results

  • Most effective for: Systemic anti-aging, wound healing

Side Effects & Safety

Side Effects

When to Stop

  • Monitor injection sites for unusual blue discoloration

  • Start with lower doses to assess copper tolerance

  • Use sterile injection technique to prevent infection

  • Watch for signs of copper toxicity (nausea, metallic taste)

  • Avoid excessive copper supplementation from other sources

  • Severe skin discoloration or persistent staining

  • Persistent metallic taste or nausea

  • Unusual fatigue or copper toxicity symptoms

  • Injection site infections or necrosis

  • Allergic reactions (rash, swelling, difficulty breathing)

Mechanism of Action & Molecular Information

Topical GHK-Cu penetrates skin layers to deliver copper directly to target tissues. Activates fibroblasts, stimulates collagen and elastin synthesis, promotes angiogenesis, and modulates inflammatory responses for optimal skin regeneration

Weight

Length

Type

404.96 Da

3 amino acids

Copper tripeptide

Amino Acid Sequence:

Gly-His-Lys

References

Research Studies

Regenerative and Protective Actions of GHK-Cu Peptide

Review | Int J Mol Sci | 2018 | PMC6073405

Comprehensive review showing GHK affects 31.2% of human genes, with 59% upregulated and 41% downregulated. Demonstrates broad regenerative potential across multiple tissue types.

VIEW STUDY—>

GHK Peptide in Skin Regeneration

Review | Biomed Res Int | 2015 | PMC4508379

GHK-Cu at 0.01-100 nM increased elastin and collagen production in human dermal fibroblasts. Demonstrates skin regeneration through multiple cellular pathways.

VIEW STUDY—>

GHK and DNA: Resetting the Genome to Health

Review | Biomed Res Int | 2014 | PMC4180391

GHK resets genes of diseased cells to healthier states. Increases DNA repair genes (47 stimulated, 5 suppressed) and reverses COPD gene expression signature.

VIEW STUDY—>

GHK-Cu in Prevention of Oxidative Stress and Aging

Review | Oxid Med Cell Longev | 2012 | PMC3359723

Cognitive enhancement demonstrated in aged mice at 10 mg/kg body weight. Shows neuroprotective and antioxidant effects with potential anti-aging applications.

VIEW STUDY—>

Important Note

This content is intended for educational purposes only and is not medical advice, diagnosis, or treatment.

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